Anti-UCK2 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution

Biochem/physiol Actions

Uridine-cytidine kinase 2 is an enzyme encoded by the UCK2 gene in humans. It is normally expressed in human placenta, but is overexpressed in certain cancer cells and is also responsible for activating a class of antitumor prodrugs. UCK2 is responsible for the phosphorylation and activation of the antitumor 3′-ethynyl nucleosides. It play an important role in activating anti-tumour pro-drugs in human cancer cells.

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Immunogen

Recombinant uridine-cytidine kinase 2

Immunogen Sequence: GI # 18699734, sequence 1-261

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.